EPHA8 Antibody | 13-505

EPHA8 Antibody | 13-505 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 28-300 of human EPHA8 (NP_001006944.1) .

Research Area: Neuroscience, Signal Transduction

Tested Application: WB

Application: WB: 1:1000 - 1:2000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: B cells

Positive Control 3: Mouse liver

Positive Control 4: Mouse heart

Positive Control 5: Mouse pancreas

Positive Control 6: Mouse brain

Molecular Weight: Observed: 111kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: EEK, EK3, HEK3, ephrin type-A receptor 8, EPH- and ELK-related kinase, EPH- and ELK-related tyrosine kinase, EPH-like kinase 3, hydroxyaryl-protein kinase, protein-tyrosine kinase, tyrosine-protein kinase receptor EEK, tyrosylprotein kinase

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.