ERAP1 monoclonal Antibody | MB63172

ERAP1 monoclonal Antibody | MB63172 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500

Background: The protein encoded by this gene is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: endoplasmic reticulum aminopeptidase 1

Molecular Weight: 107.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; PILS-AP; PILSAP

Immunogen: Human recombinant protein fragment corresponding to amino acids 529-941 of human ERAP1 (NP_001035548) produced in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A