ERCC8 Polyclonal Antibody | E-AB-62045

ERCC8 Polyclonal Antibody | E-AB-62045 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ERCC8, CKN1, CSA, UVSS2

Application: WB

Reactivity: Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Epigenetics and Nuclear Signaling

Background: This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: A synthetic peptide of human ERCC8 (NP_000073.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 23 kDa/44 kDa

Molecular Weight(Observed): 44 kDa