Description
ERCC8 Polyclonal Antibody | E-AB-62045 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: ERCC8, CKN1, CSA, UVSS2
Application: WB
Reactivity: Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Epigenetics and Nuclear Signaling
Background: This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: A synthetic peptide of human ERCC8 (NP_000073.1).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): 23 kDa/44 kDa
Molecular Weight(Observed): 44 kDa