Description
Rabbit Anti-Human ERK1 + ERK2 (pThr202 + pTyr204/pThr185 + pTyr187) Polyclonal
Additional Information
Size: |
100 µl |
Target: |
ERK1 + ERK2 (pThr202 + pTyr204/pThr185 + pTyr187) |
Conjugate: |
Unconjugated |
Research Area: |
Neuroscience | Neurodegeneration | Alzheimer's Disease | Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | MAPK Pathway | Stem Cells | Signaling Pathways | TGF Beta | Cytoplasmic | Cancer | Invasion/microenvironment | Cancer | A |
Alternative Name: |
Insulin-stimulated MAP2 kinase Antibody, Extracellular Signal Regulated Kinase 1 Antibody, EC:2.7.11.24 Antibody, p44-ERK1 Antibody, Protein Kinase Mitogen Activated 3 Antibody, PRKM3 Antibody, P44ERK1 Antibody, ERK-1 Antibody, p44-MAPK Antibody, MGC |
Category: |
Antibodies |
Product Type: |
Polyclonal Antibody |
Immunogen: |
Synthetic phospho-peptide from human ERK1 + ERK2 proteins around the phosphorylation sites of ERK1 at threonine 202 (pThr202) and tyrosine 204 (pTyr204), and ERK2 at threonine 185 (pThr185) and tyrosine 187 (pTyr187). |
Immunogen Species: |
Human |
Applications: |
WB, IHC |
Host: |
Rabbit |
Isotype: |
IgG |
Species Reactivity: |
Human, Mouse, Rat |
Antibody Dilution: |
WB (1:250-1:500); IHC (1:25-1:100); optimal dilutions for assays should be determined by the user. |
Purification: |
Peptide Affinity Purified |
Storage Buffer: |
PBS, pH 7.4, 150mM NaCl, 50% glycerol, 0.02% sodium azide |
Concentration: |
N/A |
Specificity: |
Detects endogenous levels of ERK1 only when phosphorylated at threonine 202 (pThr202) and tyrosine 204 (pTyr204), and ERK2 only when phosphorylated at threonine 185 (pThr185) and tyrosine 187 (pTyr187). Human sites: Thr202+Tyr204/Thr185+Tyr187. Mouse |
Storage: |
-20ºC |
Shipping: |
Blue Ice or 4ºC |
Certificate of Analysis: |
N/A |
Cellular Localization: |
Nucleus, Cytoplasm Caveola, Cytoplasm, Caveola, Cytoskeleton, Cytosol, Endosome, Early Endosome, Late Endosome, Extracellular Exosome, Golgi Apparatus, Mitochondrion, Nuclear Envelope, Nucleoplasm, Plasma Membrane, Focal Adhesion, Protein Complex, Ps |
Tissue Specificity: |
N/A |
Accession Number: |
NP_001035145.1/NP_002736.3 |
Gene ID: |
5595/5594 |
Swiss-Prot: |
P27361/P28482 |
Field of Use: |
For in vitro research use only. |