ERRF Antibody | 7289

ERRF Antibody | 7289 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: ERRF antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ERRF .
The immunogen is located within the last 50 amino acids of ERRF.

Research Area: Cancer, Cell Cycle

Tested Application: E, WB, IHC-P, IF

Application: ERRF Antibody can be used for detection of ERRF by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human and mouse samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1201 - HeLa Cell Lysate

Positive Control 2: Cat. No. 1288 - A20 Cell Lysate

Positive Control 3: Cat. No. 17-001 - HeLa Cell Slide

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 19 kDa
Observed: 15 kDa

Validation: N/A

Isoform: N/A

Purification: ERRF Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: ERRF Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: ERRF antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.

Alternate Name: ERRF Antibody: ERRF, Uncharacterized protein C1orf64

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.