Description
Etalocib | B3376
Description: Etalocib (LY293111) is a potent and selective inhibitor of the lipoxygenase pathway either directly through 5'-lipoxygenase or via antagonism of the leukotriene B4 (LTB4) receptor. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with an lC50 of 20 nM. LY293111 has antineoplastic activity in a variety of preclinical models.
Alternate Name/Synonyms: LY293111 2-(3-(3-((5-ethyl-4'-fluoro-2-hydroxy-[1,1'-biphenyl]-4-yl)oxy)propoxy)-2-propylphenoxy)benzoate sodium VML 295
Appearance: Solid
Formulation:
CAS Number: 161172-51-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₃H₃₂FNaO₆
Molecular Weight: 566.59
Cell-Permeable?: True
Purity: ≥98%
Solubilities: >50 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when hproduct! Avoid contact by all modes of exposure.
Tag Line: An orally active leukotriene B4 receptor antagonist
MDL Number:
PubChem CID: 177941
PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/177941
SMILES: CCCC1=C(C=CC=C1OC2=CC=CC=C2C(=O)O)OCCCOC3=CC(=C(C=C3CC)C4=CC=C(C=C4)F)O
InChi: InChI=1S/C33H33FO6/c1-3-9-25-29(12-7-13-30(25)40-31-11-6-5-10-26(31)33(36)37)38-18-8-19-39-32-21-28(35)27(20-22(32)4-2)23-14-16-24(34)17-15-23/h5-7,10-17,20-21,35H,3-4,8-9,18-19H2,1-2H3,(H,36,37)
InChi Key: YFIZRWPXUYFCSN-UHFFFAOYSA-N
Category: Biochemicals
Additional Information
Storage Conditions: |
-20ºC |
Shipping Conditions: |
Gel Pack |
Shelf life: |
36 month |