Everolimus | 1917

A derivative of the macrolide Rapamycin (Cat. No. 1568-5, 50) that acts as an immunosuppressant, mTOR inhibitor and anticancer agent. It targets the raptor mammalian target of rapamycin (mTORC1).

Everolimus is a derivative of the macrolide Rapamycin (Cat. No. 1568-5, 50) that acts as an immunosuppressant, mTOR inhibitor and anticancer agent. It targets the raptor mammalian target of rapamycin (mTORC1).

1917 | Everolimus DataSheet

Alternate Name/Synonyms: RAD-001

Appearance: Off-white solid

Formulation: N/A

CAS Number: 159351-69-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅₃H₈₃NO₁₄

Molecular Weight: 958.22

Cell-Permeable?: No

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from light and air

Country of Origin: USA

Tag Line: An immunosuppressant and mTOR inhibitor

MDL Number: MFCD07785165

PubChem CID: 6442177

SMILES: CC1CCC2CC(C(=CC=CC=CC(CC(C(=O)C(C(C(=CC(C(=O)CC(OC(=O)C3CCCCN3C(=O)C(=O) C1(O2)O)C(C)CC4CCC(C(C4)OC)OCCO)C)C)O)OC)C)C)C)OC

InChi: InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7) 53(62, 68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43 (66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36 (5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15, 18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-, 39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1

InChi Key: HKVAMNSJSFKALM-GKUWKFKPSA-N