Description
A 10 mM (5 mg in 1.60 ml) solution of the potent JAK3 inhibitor CP-690550 (Cat. No. 1622) in anhydrous DMSO.
A Janus Kinase 3 (JAK3) inhibitor. Displays greater antiproliferative and pro-apoptotic activity against murine multipotent factor-dependent cell Patersen-erythropoietin receptor (FDCP-EpoR) cells harboring JAK2(V617F) compared with JAK2(WT).
B2478 | EZSolution™ CP-690550 DataSheet
Alternate Name/Synonyms: EZSolution™ Tasocitinib; EZSolution™ Tofacitinib, (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile, 1-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo [2,3-d]pyrimidin-4-yl-3-piperidinamine
Appearance: Liquid
Formulation: A 10 mM solution in anhydrous DMSO
CAS Number: 477600-75-2
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₂₀N₆O
Molecular Weight: 312.37
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent JAK3 inhibitor
MDL Number:
PubChem CID: 9926791
SMILES: CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
InChi: InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1
InChi Key: UJLAWZDWDVHWOW-YPMHNXCESA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24months |