Description
A 10 mM (5 mg in 874 µl) solution of the of the EZH2 inhibitor EPZ6438 (Cat. No.2383) in anhydrous DMSO.
EPZ-6438 is a potent and selective inhibitor of histone methyltransferase EZH2.
2428 | EZSolution™ EPZ-6438 DataSheet
Alternate Name/Synonyms: N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-5-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-4-methyl-4'-(morpholinomethyl)-[1,1'-biphenyl]-3-carboxamide; E-7438
Appearance: Liquid
Formulation: 10 mM solution in DMSO
CAS Number: 1403254-99-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₄H₄₄N₄O₄
Molecular Weight: 572.74
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: N/A
Handling: Protect from light and air
Country of Origin: USA
Tag Line: A potent EZH2 inhibitor
MDL Number: N/A
PubChem CID: N/A
SMILES: CCN(C1CCOCC1)C2=CC(C3=CC=C(CN4CCOCC4)C=C3)=CC(C(NCC5=C(C)C=C(C)NC5=O)=O)=C2C
InChi: InChI=1S/C34H44N4O4/c1-5-38(29-10-14-41-15-11-29)32-20-28(27-8-6-26(7-9-27)22-37-12-16-42-17-13-37)19-30(25(32)4)33(39)35-21-31-23(2)18-24(3)36-34(31)40/h6-9,18-20,29H,5,10-17,21-22H2,1-4H3,(H,35,39)(H,36,40)
InChi Key: NSQSAUGJQHDYNO-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20 ̊C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |