Description
A 10 mM (5 mg in 1.38 ml) of the potent proteasome inhibitor Ixazomib (Cat. No. B2384) in anhydrous DMSO.
Ixazomib (MLN-2238), is a potent proteasome inhibitor (PI) with potential antineoplastic activity. MNL-2238 is a biologically active form of MLN9708. MLN-2238 has an improved pharmacodynamic profile and antitumor activity compared with bortezomib in both OCI-Ly10 and PHTX22L models.
B2488 | EZSolution™ Ixazomib DataSheet
Alternate Name/Synonyms: MLN-2238; MLN2238; (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)boronic acid
Appearance: Liquid
Formulation: A 10 mM solution in anhydrous DMSO
CAS Number: 1072833-77-2
Structure Available?:
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₄H₁₉BCl₂N₂O₄
Molecular Weight: 361.03
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent proteasome inhibitor
MDL Number:
PubChem CID: 25183872
SMILES: B(C(CC(C)C)NC(=O)CNC(=O)C1=C(C=CC(=C1)Cl)Cl)(O)O
InChi: InChI=1S/C14H19BCl2N2O4/c1-8(2)5-12(15(22)23)19-13(20)7-18-14(21)10-6-9(16)3-4-11(10)17/h3-4,6,8,12,22-23H,5,7H2,1-2H3,(H,18,21)(H,19,20)/t12-/m0/s1
InChi Key: MXAYKZJJDUDWDS-LBPRGKRZSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
24months |