Description
A 10 mM (5 mg in 1072 µl) of the terpenoid lactone Nimbolide (Cat. No. 1891) in anhydrous DMSO.
Nimbolide is a terpenoid lactone derived from Azadirachta indica (Neem tree) that displays a variety of biological activities including anti-malarial and anticancer activity. Recently it has also been shown that nimbolide sensitizes colon cancer cells to TRAIL-induced apoptosis.
9655 | EZSolution™ Nimbolide DataSheet
Alternate Name/Synonyms: (4α,5α,6α,7α,15β,17α)-7,15:21,23-Diepoxy-6-hydroxy-4,8-dimethyl-1-oxo-18,24-dinor-11,12-secochola-2,13,20,22-tetraene-4,11-dicarboxylic Αcid γ-lactone Methyl Ester; CCRIS 5723, NSC-309909
Appearance: Liquid
Formulation: A 10 mM solution in DMSO
CAS Number: 25990-37-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₇H₃₀O₇
Molecular Weight: 466.52
Cell-Permeable?: Yes
Purity: ≥98% by TLC
Solubilities: N/A
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An anticancer agent
MDL Number: MFCD01735386
PubChem CID: 100017
SMILES: CC1=C2C(CC1C3=COC=C3)OC4C2(C(C5(C6C4OC(=O)C6(C=CC5=O)C)C)CC(=O)OC)C
InChi: InChI=1S/C27H30O7/c1-13-15(14-7-9-32-12-14)10-16-20(13)27(4)17(11-19(29) 31-5)26(3)18(28)6-8-25(2)22(26)21(23(27)33-16)34-24(25)30/h6-9,12,15-17, 21-23H,10-11H2,1-5H3
InChi Key: JZIQWNPPBKFOPT-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |