EZSolution™ SP600125 | 9541

A 10 mM (5 mg in 2270 µl) of the JNK inhibitor SP600125 (Cat. No.1669) in anhydrous DMSO.

U0126 is a potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC₅₀ values of 0.07 and 0.06 µM respectively) with little or no effect on the activities of PKC, Abl, Raf, MEKK, ERK, JNK, MKK-3, MKK-4/SEK, MKK-6, Cdk2 or Cdk4.

9541 | EZSolution™ SP600125 DataSheet

Alternate Name/Synonyms: Anthra[1-9-cd]pyrazol-6(2H)-one

Appearance: Liquid

Formulation: 11 mM solution in anhydrous DMSO

CAS Number: 129-56-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₈N₂O

Molecular Weight: 220.23

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: N/A

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A JNK inhibitor

MDL Number: MFCD00022289

PubChem CID: 8515

SMILES: C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O

InChi: InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)

InChi Key: ACPOUJIDANTYHO-UHFFFAOYSA-N