EZSolution™ Triacsin C | 9683

EZSolution(TM) Triacsicn C, is an Inhibitor of acyl-CoA synthetase (IC₅₀ = 6.3 μM in Raji cells). Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice. It has been shown to interfere with lipid metabolism by inhibiting the de novo synthesis of triglycerides, diglycerides, and cholesterol esters.

Triacsicn C, originally isolated from Streptomyces sp. is an Inhibitor of acyl-CoA synthetase (IC₅₀ = 6.3 μM in Raji cells). Inhibits lipid synthesis and cell proliferation in Raji lymphoma cells. Induces apoptosis in cancer cell lines and inhibits human lung cancer cell xenograft tumor growth in mice. It has been shown to interfere with lipid metabolism by inhibiting the de novo synthesis of triglycerides, diglycerides, and cholesterol esters.

9683 | EZSolution™ Triacsin C DataSheet

Alternate Name/Synonyms: (2E,4E,7E)-2,4,7-Undecatrienal nitrosohydrazone

Appearance: Liquid

Formulation: In DMSO (1 mg/ml)

CAS Number: 76896-80-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₁H₁₇N₃O

Molecular Weight: 207.27

Cell-Permeable?: Yes

Purity: ≥90% by TLC

Solubilities: N/A

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An acyl-CoA synthetase inhibitor

MDL Number: MFCD00798237

PubChem CID: 9576787

SMILES: CCCC=CCC=CC=CC=NNN=O

InChi: InChI=1S/C11H17N3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h4-5,7-11H,2-3,6H2,1H3,(H,13,15)/b5-4+,8-7+,10-9+,12-11+

InChi Key: NKTGCVUIESDXPU-YLEPRARLSA-N