Description
FABP2 polyclonal Antibody | BS6602 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IF
Application Range: WB 1:500 - 1:2000 IF 1:10 - 1:100
Background: Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP) . Intestinal FABP (I-FABP) is an abundant cytosolic protein abundant in small intestine epithelial cells. The human gene maps to chromosome 4q26 and has a polymorphism at codon 54, which confers an alanine-encoding allele and a threonine-encoding allele. Threonine at position 54 is associated with increased fat oxidation and Insulin resistance.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FABP2 polyclonal Antibody detects endogenous levels of FABP2 protein.
Molecular Weight: ~15 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FABP 2; FABP2; FABPI; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein; Fatty acid binding protein intestinal; Fatty acid-binding protein 2; Fatty acid-binding protein; I FABP; I-FABP; IFABP; intestinal; Intestinal fatty acid binding protein 2; Intestinal-type fatty acid-binding protein; MGC133132; OTTHUMP00000163925;
Immunogen: Recombinant full length Human FABP2.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: