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Factor H polyclonal Antibody | BS90490
- SKU:
- BW-BS90490
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- Usually ships in 5 working days
Description
Factor H polyclonal Antibody | BS90490 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB ICC
Application Range: WB:1:500-1:2,000 ICC:1:50-1:200
Background: The Factor H gene family is a multidomain, multifunctional protein family whose individual members are defined by conserved structural elements, which display diverse yet often overlapping functions. These proteins share a common structural motif, the short consensus repeat (SCR), which is structurally conserved among related genes and between phylogenetically divergent species. The human complement Factor H (FH, CFH, HUS, b-1H) gene encodes a 1213 amino acid serum glycoprotein which is arranged into 20 SCRs, each approximately 60 amino acids long, and an 18-residue leader sequence. Factor H controls the function of the alternative complement pathway and acts as a cofactor with Factor I (C3b inactivator) . In addition, Factor H has functional activity outside of the complement system, where it can bind to the cellular integrin receptor (CD11b/CD18), interact with cell surface glycosaminoglycans and associate with the surface of certain pathogenic microorganisms. Deficiencies in Factor H is a common characteristic of acute renal disease.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Factor H polyclonal Antibody detects endogenous levels of Factor H protein.
Molecular Weight: 140 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CFH, HF, HF1, HF2, adrenomedullin binding protein, age related maculopathy susceptibility 1, AHUS 1, AHUS1, AMBP 1, AMBP1, ARMD 4, ARMD4, ARMS 1, ARMS1, beta 1 H globulin, beta 1H, beta1H, CFAH, CFH, CFHL 3, CFHL3, Complement factor H, complement factor H, isoform b, Factor H, factor H like 1, FH, FHL 1, FHL1, H factor 1 (complement), H factor 1, H factor 2 (complement), HF 1, HF 2, HF, HF1, HF2, HUS, MGC88246,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: