Fadrozole | B2536

Fadrozole is a potent, nonsteroidal aromatase inhibitor with potential antineoplastic activity. Fadrozole specifically inhibits aromatase, blocking the aromatization of androstenedione and testosterone into estrone and estradiol, respectively, the final step in estrogen biosynthesis; the reduction in estrogen levels may inhibit growth in estrogen-dependent cancers.

Fadrozole is a potent, nonsteroidal aromatase inhibitor with potential antineoplastic activity. Fadrozole specifically inhibits aromatase, blocking the aromatization of androstenedione and testosterone into estrone and estradiol, respectively, the final step in estrogen biosynthesis; the reduction in estrogen levels may inhibit growth in estrogen-dependent cancers.

B2536 | Fadrozole DataSheet

Alternate Name/Synonyms: Afema; 4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)-benzonitrile; CGS 16949A

Appearance: Off-white solid

Formulation:

CAS Number: 102676-47-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₄H₁₃N₃

Molecular Weight: 223.27

Cell-Permeable?: True

Purity: ≥98%

Solubilities: in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: An aromatase inhibitor

MDL Number:

PubChem CID: 59693

SMILES: C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N

InChi: InChI=1S/C14H13N3/c15-8-11-4-6-12(7-5-11)14-3-1-2-13-9-16-10-17(13)14/h4-7,9-10,14H,1-3H2

InChi Key: CLPFFLWZZBQMAO-UHFFFAOYSA-N