FAK2/PYK2B, Human Recombinant | P1416

FAK2 is a cytoplasmic tyrosine kinase involved in calcium-induced regulation of ion channels and activation of the MAP kinase signaling pathway. It regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. The protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity

P1416 | FAK2/PYK2B, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: PTK2B, CAK beta, Protein-tyrosine kinase 2-beta

Alternates names: PTK2B, CAK beta, Protein-tyrosine kinase 2-beta

Taglines: Protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion.

NCBI Gene ID #: PTK2B

NCBI Gene Symbol: 2185

Gene Source: Human

Accession #: Q14289

Recombinant: False

Source: Baculovirus (sf9 Insect Cells)

Purity by SDS-PAGE: >95%

Assay: SDS-PAGE

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method): >20 U/ug (nmol/min/ug) measured by using ADPsensorâ„¢ Universal Kinase Activity Assay Kit K212-100

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 76.2 kDa (contains N-His tag).

Concentration:

Appearance: Liquid

Physical form description:

Reconstitution Instructions:

Amino acid sequence: aa 360-1009

Handling: Centrifuge the vial prior to opening.

Usage: