FAM173B polyclonal Antibody | BS8883

FAM173B polyclonal Antibody | BS8883 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB 1:500 - 1:2000

Background: FAM173B is a 233 amino acid single-pass membrane protein that is encoded by a gene that maps to human chromosome 5, which makes up about 6% of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FAM173B polyclonal Antibody detects endogenous levels of FAM173B protein.

Molecular Weight: ~ 26kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Protein FAM173B; FAM173B

Immunogen: Recombinant full length Human FAM173B.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: