BW
FARSLB polyclonal Antibody | BS60426
- SKU:
- BW-BS60426
- Availability:
- Usually ships in 5 working days
Description
FARSLB polyclonal Antibody | BS60426 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: FARSLB (Phenylalanine--tRNA ligase beta chain), also known as FARSB, FRSB, PheHB or PheRS, is a 589 amino acid cytoplasmic protein that is the regulatory beta subunit of phenylalanine-tRNA synthetase. A highly conserved member of the aminoacyl-tRNA synthetase class IIc subfamily, FARSLB functions to enzymatically attach L-phenylalanine residues to terminal adenosines on tRNA (Phe) . This is an ATP-dependent reaction that yields AMP, a diphosphate and an L-phenylalanine-tagged tRNA (Phe) . FARSLB is expressed in brain, heart, kidney, pancreas, placenta and skeletal muscle and its expression is increased in malignant cell lines, suggesting a possible role for FARSLB in carcinogenesis.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: FARSLB polyclonal Antibody detects endogenous levels of FARSLB protein.
Molecular Weight: ~ 80 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Phenylalanine--tRNA ligase beta subunit; Phenylalanyl-tRNA synthetase beta subunit; PheRS; FARSB; FARSLB; FRSB; HSPC173
Immunogen: A synthetic peptide corresponding to residues in Human FARSLB.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: TGFβ Smad signaling,