FASTKD2 Antibody (Center) [APR32744G]

FASTKD2 Antibody (Center) [APR32744G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This FASTKD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318~347 amino acids from the Central region of human FASTKD2.

Cellular Localisation: Mitochondrion matrix, mitochondrion nucleoid Mitochondrion matrix. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.

Molecular Weight: 81463

Clone: Polyclonal

Gene Name: FASTKD2 {ECO:0000303|PubMed:27667664, ECO:0000312|HGNC:HGNC:29160}

Gene ID: 22868

Function: Plays an important role in assembly of the mitochondrial large ribosomal subunit (PubMed:25683715) . As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt- rRNA), controls 16S mt-rRNA abundance and is required for intra- mitochondrial translation (PubMed:27667664, PubMed:25683715, PubMed:26370583) . May play a role in mitochondrial apoptosis.

Summary: Tissue Location: Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle and thyroid.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: FAST kinase domain-containing protein 2, FASTKD2, KIAA0971