Description
FBXL16 Antibody | 6165 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: FBXL16 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human FBXL16.
The immunogen is located within the last 50 amino acids of FBXL16.
Research Area: Cancer, Cell Cycle
Tested Application: E, WB, IHC-P, IF
Application: FBXL16 antibody can be used for detection of FBXL16 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Specificiy: FBXL16 antibody is predicted to not cross-react with other F-box protein family members.
Positive Control 1: Cat. No. 1306 - Human Spleen Tissue Lysate
Positive Control 2: Cat. No. 10-901 - Human Spleen Tissue Slide
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: FBXL16 Antibody is affinity chromatography purified via peptide column.
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: FBXL16 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: FBXL16 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: FBXL16 Antibody: Fbl16, C16orf22, c380A1.1, FBL16, F-box and leucine-rich repeat protein 16
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FBXL16 Antibody: FBXL16 (F-box and leucine-rich repeat protein 16) , a member of the F-box protein family, is a probable substrate-recognition component of the SCF (SKP1-CUL1-F-box protein) -type E3 ubiquitin ligase complex. It is characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F-box, and they interact with ubiquitination targets through other protein interaction domains. FBXL16 is a novel E2F1-regulated gene in crucial cell cycle regulation pathways.