FBXO32 Polyclonal Antibody | E-AB-17885

FBXO32 Polyclonal Antibody | E-AB-17885 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: 4833442G10Rik, AI430017, Atrogin 1 , Atrogin-1, ATROGIN1, Atrophy gene 1, F box only protein 32, F-box only protein 32, F-box protein 32, FBX32, fbxo25, FBXO32, FLJ32424, MAFbx, MGC108443, MGC137646, MGC33610 , Muscle atrophy F box, Muscle atrophy F box protein, Muscle atrophy F-box protein

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

Concentration: 1.98 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human FBXO32

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A