FBXO45 Antibody (N-Term) [ApR04831G]

FBXO45 Antibody (N-Term) [ApR04831G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This FBXO45 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 83-115 amino acids from human FBXO45.

Cellular Localisation: Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, presynaptic cell membrane

Molecular Weight: 30633

Clone: Polyclonal

Gene Name: FBXO45

Gene ID: 200933

Function: Component of E3 ubiquitin ligase complexes. Required for normal neuromuscular synaptogenesis, axon pathfinding and neuronal migration (By similarity) . Plays a role in the regulation of neurotransmission at mature neurons (By similarity) . May control synaptic activity by controlling UNC13A via ubiquitin dependent pathway (By similarity) . Specifically recognizes TP73, promoting its ubiquitination and degradation.

Summary: N/A

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: F-box/SPRY domain-containing protein 1, F-box only protein 45, hFbxo45, FBXO45, FBX45