FBXW5 Polyclonal Antibody | E-AB-68018

FBXW5 Polyclonal Antibody | E-AB-68018 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: FBXW5, Fbw5

Application: WB

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human FBXW5 (NP_061871.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 42 kDa/63 kDa

Molecular Weight(Observed): 72 kDa