Felodipine | 2399

A potent L-type Ca²⁺channel blocker that is selective over N-, R-, P/Q- and T-type channels. It displays high vascular selectivity over cardiac muscle, thus lowering arterial blood pressure without altering cardiac contractility. Felodipine is used in the clinic as an antihypertensive agent.

Felodipine is a potent L-type Ca²⁺ channel blocker that is selective over N-, R-, P/Q- and T-type channels.

2399 | Felodipine DataSheet

Alternate Name/Synonyms: 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Appearance: White solid

Formulation: N/A

CAS Number: 72509-76-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₉Cl₂NO₄

Molecular Weight: 384.25

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (~35 mg/ml) or EtOH (~ 35 mg/ml)

Handling: Protect from light and air

Country of Origin: USA

Tag Line: A potent L-type Ca²⁺channel blocker

MDL Number: MFCD00868316

PubChem CID: 3333

SMILES: CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C

InChi: InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3

InChi Key: RZTAMFZIAATZDJ-UHFFFAOYSA-N