FGF-5, human recombinant | 7147

FGF-5 is a secreted heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle. Recombinant human FGF-5 is a 27.6 kDa protein consisting of 252 amino acid residues.

7147 | FGF-5 human recombinant DataSheet

Biomolecule/Target: FGF-5

Synonyms: Fibroblast Growth Factor-5, HBGF-5, Smag-82

Alternates names: PTH/PTHrP receptor antagonist, PTHrP analog, PTHR, MGC138426, MGC138452

Taglines: Promotes cellular proliferation and differentiation

NCBI Gene ID #: 5744

NCBI Gene Symbol: PTHLH

Gene Source: Human

Accession #: P12272

Recombinant: Yes

Source: E. coli.

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: HPLC

Endotoxin Level: < 0.1 ng/g of protein (<1EU/g).

Activity (Specifications/test method): Determined by the dose dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is 0.5 ng/ml corresponding to a specific activity of 2 x 10^6 units/mg.

Biological activity: Test in process

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 9.8 kDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Sterile filtered through a 0.2 micron filter. Lyophilized from 5 mM Tris, pH 7.5, and 25 mM NaCl.

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A