FGF2 | Basic fibroblast growth factor | IMS01-138-313

FGF2 | Basic fibroblast growth factor | IMS01-138-313 | Gentaur UK, US & Europe Distribution

Immunogen: purified full length native protein UniProt:P09038

Host: Chicken

Conjugation: N/A

Clonality: Polyclonal

Isotype: N/A

Purity: Purified, total IgY (chicken egg yolk immunoglobulin) in 0.9% NaCl, 0.02% sodium azide.

Format: Liquid

Tested Application: Total, purified IgY

Related Products: N/A

Recommended Dilutions: 1 : 1000 (ELISA), 1 : 1000 (WB)

Molecular weight: 18 kDa

Confirmed Reactivity: Human

Predicted Reactivity: Bovine, Chicken, Mouse, Rat, Sheep

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: Reacts with human recombinant FGF2, No reactivity with other human serum proteins

Background: Basic Fibroblast Growth Factor (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Reconstitution: N/A

Storage: Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

TAIR Nnumbre: N/A

Category: Cancer

Research Area: Cancer Research