FGF5 polyclonal Antibody | BS61521

FGF5 polyclonal Antibody | BS61521 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithe-lial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10–FGF-23. Members of the FGF family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family including four tyrosine kinases, designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3. FGF-5, also designated Smag-82 and HBGF-5 was identified as the product of an oncogene and the protein is expressed in neonatal brain. Alternative splicing results in long and short isoforms (FGF-5S) of the protein where the C-terminal residues 124-268 are missing in the truncated FGF-5S.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FGF5 polyclonal Antibody detects endogenous levels of FGF5 protein.

Molecular Weight: ~ 30 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Fibroblast growth factor 5; FGF-5; Heparin-binding growth factor 5;HBGF-5; Smag-82

Immunogen: Synthetic peptide, corresponding to amino acids 224-268 of Human FGF5.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)

Pathway: