FGFR1 OP (N371) polyclonal Antibody | BS1123

FGFR1 OP (N371) polyclonal Antibody | BS1123 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: IHC IF

Application Range: IHC: 1:50~1:200 IF: 1:50~1:200

Background: FOP, also known as FGFR1OP (FGFR1 oncogene partner), is a 399 amino acid protein that localizes to the centrosome and contains one LisH domain. Expressed ubiquitously with highest expression in kidney, heart, muscle, colon, liver, testis and pancreas, FOP functions as a homodimer that interacts with EB1 and CEP350 and is essential for anchoring microtubules to centrosomes. Chromosomal aberrations that involve the FOP gene are associated with the pathogenesis of stem cell myeloproliferative disorder (MPD), a condition that is characterized by eosinophilia and myeloid hyperplasia and ultimately leads to acute myeloid leukemia. FOP is expressed as multiple isoforms that are produced by alternative splicing events.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FGFR1OP (N371) polyclonal Antibody detects endogenous levels of FGFR1OP protein.

Molecular Weight: ~ 43, 92 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FGFR1 oncogene partner; FGFR1OP; Fibroblast growth factor receptor 1 oncogene partner; FOP

Immunogen: Synthetic peptide, corresponding to amino acids 341-390 of Human FGFR1 OP.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Pathway: