FGFR1OP2 Polyclonal Antibody | E-AB-11233

FGFR1OP2 Polyclonal Antibody | E-AB-11233 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: DKFZp564O1863, FGFR1 oncogene partner 2, FGFR1OP2, FGOP2, Fibroblast growth factor receptor 1 oncogene partner 2, HSPC123, HSPC123 like, WIT3.0, Wound inducible transcript 3.0

Application: IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cell Biology

Background: Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors which include the Flg receptor (FGFR-1) and the Bek receptor (FGFR-2), as well as FGFR-3, FGFR-4, FGFR-5 and FGFR-6. FGFR1OP2 (FGFR1 oncogene partner 2), also known as HSPC123, is a 253 amino acid cytoplasmic protein that is expressed in spleen, thymus and bone marrow and is involved in wound healing under normal cellular conditions. Additionally, FGFR1OP2 may also exist as an aberrant fusion protein with Flg and it is thought that the FGFR1OP2-Flg mutant may play a role in the pathogenesis of stem cell myeloproliferative disorder (MPD). Multiple isoforms of FGFR1OP2 exist due to alternative splicing events.

Concentration: 0.7 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human FGFR1OP2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A