FGL1 Antibody (C-term) [APR03724G]

FGL1 Antibody (C-term) [APR03724G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This FGL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-247 amino acids from the C-terminal region of human FGL1.

Cellular Localisation: Secreted. Note=Secreted in the blood plasma

Molecular Weight: 36379

Clone: Polyclonal

Gene Name: FGL1 {ECO:0000303|PubMed:18039467, ECO:0000312|HGNC:HGNC:3695}

Gene ID: 2267

Function: Immune suppressive molecule that inhibits antigen-specific T- cell activation by acting as a major ligand of LAG3 (PubMed:30580966) . Responsible for LAG3 T-cell inhibitory function (PubMed:30580966) . Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966) . Secreted by, and promotes growth of, hepatocytes (PubMed:11470158, PubMed:19880967) .

Summary: Tissue Location: Under normal conditions, liver-specific.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: IHC-P, WB

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Fibrinogen-like protein 1, HP-041, Hepassocin, Hepatocyte-derived fibrinogen-related protein 1, HFREP-1, Liver fibrinogen-related protein 1, LFIRE-1, FGL1, HFREP1