FH Antibody (N-term) [AMM04545G]

FH Antibody (N-term) [AMM04545G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This FH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-135 amino acids from the N-terminal region of human FH.

Cellular Localisation: [Isoform Mitochondrial]: Mitochondrion

Molecular Weight: 54637

Clone: Polyclonal

Gene Name: FH {ECO:0000303|PubMed:27037871, ECO:0000312|HGNC:HGNC:3700}

Gene ID: 2271

Function: Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (PubMed:30761759) . Experiments in other species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable) .

Summary: Tissue Location: Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non-spherocytic hemolytic anemia of unknown etiology.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000 IHC--1:800

Synonyms: Fumarate hydratase, mitochondrial, Fumarase, FH