FH (Fumarate Hydratase) monoclonal Antibody | MB63300

FH (Fumarate Hydratase) monoclonal Antibody | MB63300 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat, Dog

Application: IF, WB

Application Range: WB 1:2000, IF 1:50~100

Background: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq]

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: fumarate hydratase

Molecular Weight: 50.2 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: FMRD; HLRCC; LRCC; MCL; MCUL1

Immunogen: Full length human recombinant protein of human FH (NP_000134) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A