Fibrillin Antibody [11C1.3] (Biotin) | 98-521

Fibrillin Antibody [11C1.3] (Biotin) | 98-521 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Bovine, Japanese Macaque

Homology: N/A

Immunogen: Microfibrils from the zonular apparatus of bovine eye

Research Area: Cancer, Signal Transduction

Tested Application: IHC-P, Flow

Application: Fibrillin Antibody [11C1.3] for use in immunohistochemistry / immunocytochemistry, electron microscopy, western blotting, and immunoprecipitation assays.

Specificiy: Fibrillin

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [11C1.3]

Isotype: IgG1

Conjugate: Biotin

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: 0.2 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: FBN1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear. There is an aberrant expression of fibrillin in Marfan syndrome. The epitope for the monoclonal antibody 11C1.3 has been found to be within exons 18-20 (a.a. 723-909) .