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Fibrinogenγ polyclonal Antibody | BS90513
- SKU:
- BW-BS90513
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Description
Fibrinogenγ polyclonal Antibody | BS90513 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human
Application: WB IHC FC
Application Range: WB:1:5,000-1:10,000 IHC:1:50-1:200 FC:1:50-1:100
Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.
Specificity: Fibrinogenγ polyclonal Antibody detects endogenous levels of Fibrinogenγ protein.
Molecular Weight: 52 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FGG, FGG, FIBG, Fibrinogen gamma chain, Fibrinogen gamma polypeptide, fibrinogen gamma-b chain,
Immunogen: N/A
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: