BW
Fibulin-1 polyclonal Antibody | BS60154
- SKU:
- BW-BS60154
- Availability:
- Usually ships in 5 working days
Description
Fibulin-1 polyclonal Antibody | BS60154 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB
Application Range: WB: 1:500~1:1000
Background: Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes and blood. Fibulin-1 self associates as well as binds to calcium, fibronectin, laminin, nidogen and fibrinogen. These interactions, individually or in combination, may account for the observed association of Fibulin-1 with basement membranes, connective tissue, elastic fibers and fibrin clots. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. Other studies point to the inhibition of cancer cell motility with increasing exposure to Fibulin-1. The exact function of Fibulin-1 in the cell is unknown.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Fibulin-1 polyclonal Antibody detects endogenous levels of Fibulin-1 protein.
Molecular Weight: ~ 77 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Fibulin1; Fibulin 1; FIBL1; FBLN1; PP213
Immunogen: A synthetic peptide corresponding to residues in Human Fibulin-1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: