Fibulin5 Antibody [3F10A5 / 3F8A12] | 32-155

Fibulin5 Antibody [3F10A5 / 3F8A12] | 32-155 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Ni-NTA purified truncated recombinant Fibulin 5 expressed in E. Coli strain BL21 (DE3) .

Research Area: Other

Tested Application: E, WB, IHC

Application: Western Blot:1:500 - 1:2000
IHC (P) :1:500 - 1:2000
IHC (F) :1:500 - 1:2000
ELISA:Propose dilution 1:10, 000.
Determining optimal working dilutions by titration test.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: 3F10A5 / 3F8A12

Isotype: IgG1

Conjugate: Unconjugated

Physical State: N/A

Buffer: Ascitic fluid containing 0.03% sodium azide.

Concentration: N/A

Storage Condition: Fibulin 5 monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: DANCE, UNQ184/PRO210, Developmental arteries and neural crest EGF-like protein, FIBL-5, EVEC, UP50, ADCL2, ARMD3, DANCE, ARCL1A

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: Fibulin 5 (FBLN5) , with 448-amino acid protein (about 50 kDa) , is a recently discovered multifunctional extracellular matrix protein that mediates endothelial cell adhesion through integrin ligation, regulates cell growth and motility in a context-specific manner, and prevents elastinopathy in vivo. Fibulin-5 is abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult tissues including the aorta, lung, uterus and skin, all of which contain abundant elastic fibres. Decreased fibulin-5 may contribute to the pathogenesis of aortic dissection by impairing elastic fiber assembly. Fibulin-5 is also a good marker of skin ageing and that the earlier loss of fibulin-5 may involve age-dependent changes in other elastic fibre components.