Filastatin | B2767

Filastatin is a nontoxic inhibitor of adhesion to human cells. Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.

Filastatin is a nontoxic inhibitor of adhesion to human cells. Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.

B2767 | Filastatin DataSheet

Alternate Name/Synonyms: (3-Chloro-4-methylphenyl)[4-(4-nitrophenyl)-1-piperazinyl]-methanone

Appearance: White to off-white solid

Formulation:

CAS Number: 431996-53-1

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₈H₁₈ClN₃O₃

Molecular Weight: 359.81

Cell-Permeable?: TRUE

Purity: ≥98%

Solubilities: ~15 mg/ml DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A nontoxic inhibitor of adhesion to human cells

MDL Number:

PubChem CID: 2911546

SMILES: O=C(C1=CC=C(C)C(Cl)=C1)N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2

InChi: InChI=1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3

InChi Key: PNECWWUOUHGWQG-UHFFFAOYSA-N