FKBP3 Antibody | 22-545

FKBP3 Antibody | 22-545 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human FKBP3 (NP_002004.1) .

Research Area: Other

Tested Application: WB, IF, IP

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:100
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: HeLa

Positive Control 2: MCF-7

Positive Control 3: BT-474

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 30kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-3, Immunophilin FKBP25, FK506-binding protein 3, FK506-binding protein 3 (25kD) , PPIase FKBP3, Rapamycin binding protein, Rotamase, PPIase, FK506 binding protein 3, 25kDa, FKBP-25, FKBP25

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.