Description
FKRP Antibody | 13-491 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-220 of human FKRP (NP_077277.1) .
Research Area: Signal Transduction
Tested Application: WB, IHC
Application: WB: 1:1000 - 1:3000
IHC: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: LO2
Positive Control 3: A-549
Positive Control 4: HT-29
Positive Control 5: 293T
Positive Control 6: N/A
Molecular Weight: Observed: 45kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Fukutin-related protein, 2---, FKRP
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in this gene have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.