FLNA Polyclonal Antibody | E-AB-11240

FLNA Polyclonal Antibody | E-AB-11240 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ABP 280, ABP-280, Actin-binding protein 280, Alpha filamin, Alpha-filamin, APBX, CSBS, CVD1, Endothelial actin binding protein, Endothelial actin-binding protein, Filamin 1, Filamin A alpha, Filamin A, Filamin-1, Filamin-A, FLN, FLN-A, FLN1, FLNA, FLNA, FMD, MNS, NHBP, Non muscle filamin, Non-muscle filamin, OPD, OPD1, OPD2, XLVD, XMVD

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal Transduction

Background: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human FLNA

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 281 kDa

Molecular Weight(Observed): N/A