The fluorescent control liposomes contain the lipophilic dye Dil incorporated in the bilayers. It has comparable physical and chemical attributes as for the Clophosome® except no active is encapsulated inside. It is used for tracking the cellular uptake of the liposomes by common methods like confocal, FACS, etc.
Specifications
Lipid composition: phosphatidylcholine and cholesterol
Dye: 0.15 mM (0.14mg/mL) (note: the amount of dye has increased from 0.07mg/mL to 0.14mg/mL)
Stability: 6 months for unopened vials
‘DiI’; DiIC18(3) is a lipophilic membrane dye. It is weakly fluorescent until incorporated into liposome membranes. This orange—red-fluorescent dye, which is spectrally similar to tetramethylrhodamine, is often used as a long-term tracer for neuronal and other cells.
Ex/Em: 550nm/570nm
CAS Name/Number: 3H-Indolium, 2-[3-(1,3-dihydro-3,3-dimethyl-1-octadecyl-2H-indol-2-ylidene)-1-propenyl]-3,3-dimethyl 1-octadecyl-, perchlorate/ 41085-99-8