FNDC3B Polyclonal Antibody | E-AB-52260

FNDC3B Polyclonal Antibody | E-AB-52260 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: DKFZp686D14170 , DKFZp762K137, Factor for adipocyte differentiation 104, FAD104, fibronectin type III domain containing 3B , FLJ23399, HCV NS5A binding protein 37 , MGC10002, NS5ABP37, PRO4979, YVTM2421

Application: IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Signal transduction, Stem cells

Background: Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1, 204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.

Concentration: 1.8 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A