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Fodrin α polyclonal Antibody | BS90523
- SKU:
- BW-BS90523
- Availability:
- Usually ships in 5 working days
Description
Fodrin α polyclonal Antibody | BS90523 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB IHC
Application Range: WB:1:500-1:2,000 IHC:1:50-1:200
Background: Alpha Fodrin also named Spectrin. Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous α and β chains, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers. Spectrin α I and spectrin β I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β II (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Activation of calpain results in the breakdown of spectrin α II, a neuronal cytoskeleton protein.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Fodrin α polyclonal Antibody detects endogenous levels of Fodrin α protein.
Molecular Weight: 285/150 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: NEAS, SPTA2, (ALPHA) II-SPECTRIN, Alpha II Spectrin, Alpha-II spectrin Antibodybrain, EIEE5, FLJ17738, FLJ44613, Fodrin alpha chain, Fodrin, alpha, NEAS, Non erythrocytic spectrin alpha, non-erythroid alpha chain, SPECA, Spectrin alpha chain, Spectrin alpha chain brain, Spectrin alpha non erythrocytic 1, Spectrin, Spectrin non erythroid alpha chain, Spectrin, alpha, non-erythrocytic 1 (alpha-fodrin), Spectrin, nonerythroid, alpha subunit, Spna2, SPTA 2, SPTA2, SPTA2, SPTAN 1, SPTAN1,
Immunogen: Recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: