BW
Fra-1 (D134) polyclonal Antibody | BS1933
- SKU:
- BW-BS1933
- Availability:
- Usually ships in 5 working days
Description
Fra-1 (D134) polyclonal Antibody | BS1933 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse,Rat
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Fra-1 (D134) polyclonal Antibody detects endogenous levels of Fra-1 protein.
Molecular Weight: ~ 30, 42 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Fos-related antigen 1; FRA-1; FOSL1; FRA1
Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human Fra-1.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: