Frizzled-10 (L164) polyclonal Antibody | BS2601

Frizzled-10 (L164) polyclonal Antibody | BS2601 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background: This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.Frizzled 10 is expressed during development in embryonic limbs, neural tube, and central nervous system. It has been reported to be expressed in brain, embryo, kidney, liver, lung and pancreas.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Frizzled-10 (L164) polyclonal Antibody detects endogenous levels of Frizzled-10 protein.

Molecular Weight: ~ 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Frizzled-10; Fz-10; hFz10; FzE7; CD350; FZD10

Immunogen: Synthetic peptide, corresponding to amino acids 132-180 of Human Frizzled-10.

Conjugate: N/A

Modification: N/A

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: N/A