FTO, human recombinant | 7557

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

7557 | FTO human recombinant DataSheet

Biomolecule/Target: FTO

Synonyms: Fat Mass and Obesity-associated Protein; FATSO.

Alternates names: Fat Mass and Obesity-associated Protein; FATSO.

Taglines: The gene responsible for mouse ‘fused toes’ mutation.

NCBI Gene ID #: 2253

NCBI Gene Symbol: FGF-8

Gene Source: Human

Accession #: P55075

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: ~65 kDa (SDS-PAGE). Human FTO (aa 2-505) is fused at the N-terminus to a His-tag.

Concentration: 0.2 mg/ml

Appearance: Liquid

Physical form description: 0.2 mg/ml of 0.2 m-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl.

Reconstitution Instructions: N/A

Amino acid sequence: N/A