BW
FUBP1 polyclonal Antibody | BS90540
- SKU:
- BW-BS90540
- Availability:
- Usually ships in 5 working days
Description
FUBP1 polyclonal Antibody | BS90540 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB ICC/IF IHC FC
Application Range: WB:1:1,000-1:2,000 ICC:1:100-1:500 IHC:1:50-1:200 FC:1:50-1:100
Background: Activation of FUSE, the far upstream element, is required for the proper ex-pression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP1 (FUSE-binding protein or far upstream element-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP1 functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL-60 cells, FBP1 (FBP), FBP2 and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxyl-terminal activation domains. Expression of FBP1 is detected in undifferentiated cells and is substantially decreased following cellular differentiation.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: FUBP1 polyclonal Antibody detects endogenous levels of FUBP1 protein.
Molecular Weight: 74 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: FBP, FUSE-binding protein 1, hDH V, FUBP1, DNA helicase V, far upstream element (FUSE) binding protein 1, Far upstream element (FUSE) binding protein 4, Far upstream element binding protein 1, far upstream element binding protein, Far upstream element-binding protein 1, FBP, FUBP, Fubp1, FUBP1, Fubp4, FUSE binding protein 1, FUSE-binding protein 1, HDH V,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: