Funalenone | B3225

Funalenone, a phenalene compound isolated from mycelium of Aspergillus niger FO-5904, acts as an inhibitor of type I collagenase (MMP-1). Funalenone inhibits 50% of type I collagenase activity at a concentration of 170 µM but inhibits 18.3% and 38.7% against 72 kDa and 92 kDa type IV collagenase, respectively, at a concentration of 400 µM.

Funalenone, a phenalene compound isolated from mycelium of Aspergillus niger FO-5904, acts as an inhibitor of type I collagenase (MMP-1). Funalenone inhibits 50% of type I collagenase activity at a concentration of 170 µM but inhibits 18.3% and 38.7% against 72 kDa and 92 kDa type IV collagenase, respectively, at a concentration of 400 µM.

B3225 | Funalenone DataSheet

Alternate Name/Synonyms: 3,4,7,9-Tetrahydroxy-6-methyl-1H-phenalen-1-one

Appearance: Crystalline solid

Formulation:

CAS Number: 259728-61-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₅H₁₂O₆

Molecular Weight: 288.3

Cell-Permeable?: TRUE

Purity: ≥95%

Solubilities: DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A MMP-1 inhibitor

MDL Number:

PubChem CID: 312243941

SMILES: O=C1C(OC)=C(O)C2=C(O)C=C(C)C3=C2C1=C(O)C=C3O

InChi: InChI=1S/C15H12O6/c1-5-3-6(16)10-12-9(5)7(17)4-8(18)11(12)14(20)15(21-2)13(10)19/h3-4,16-19H,1-2H3

InChi Key: QAPJKCNKHLDDAK-UHFFFAOYSA-N